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Establish a Comprehensive Multi-Organ Allocation Policy 2025

eye iconAt a glance

Background

Some organ donors are able to donate several organs: a heart, lungs, liver, intestine, two kidneys, and a pancreas. Additionally, some transplant candidates need multiple organs, like a heart-liver transplant, or a liver-kidney transplant. OPTN Policy dictates when some organs need to be offered together to one candidate but does not list a standard order across different organ-specific match runs. Current multi-organ allocation policy contributes to limited access to transplant for some single-organ candidates, such as pediatric, medically urgent, and highly sensitized candidates. Organ Procurement Organizations (OPOs) report having to spend a lot of time determining how to allocate multi-organ combinations from donors. There has been wide community support for standardizing multi-organ allocation and promoting equity in access for multi-organ and single-organ transplant candidates.

Supporting presentation

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Proposed changes

  • The Committee has developed seven multi-organ donor allocation tables to establish consistent allocation of organs from donors with at least two different organs available for donation.
  • The seven multi-organ donor allocation tables would account for approximately 98% of deceased donors who donate to multi-organ recipients, based on data from July 2023-June 2024.
  • In order to make allocation fairer, the Committee is proposing that some single-organ candidates, such as pediatric, medically urgent, and highly sensitized candidates, have priority over some multi-organ combinations.
  • To help make the complex rules for multi-organ transplants easier to follow, a computer-generated plan would be created for each donor that would guide OPOs and transplant teams step-by-step through the allocation process. It is expected that the computer-generated plans would be created for roughly 80% of organ donor match runs.
  • Lastly, the Committee proposes developing training for OPOs and transplant teams before the new policy starts, to help them adjust and follow the new rules. After the policy is in place, it will be important to closely monitor how things are going.

Anticipated impact

  • What it's expected to do
    • Promote equitable access to transplants among multi-organ and single-organ transplant candidates
    • Promote transparent, consistent and efficient allocation across all OPOs

Terms to know

  • Multi-organ allocation: offering more than one organ from a deceased donor to the same waitlist candidate.
  • Multi-organ donor allocation plan: a computer-generated donor-specific plan to guide the user through the applicable multi-organ allocation table.
  • Multi-organ donor allocation table: a table in OPTN Policy directing the order in which OPOs make offers across organ-specific match runs when a donor has more than one organ at least two different organs available for donation.
  • Match run: computerized ranking of transplant candidates based upon donor and candidate medical compatibility and criteria defined in OPTN Policy.

Click here to search the OPTN glossary


Read the full proposal (PDF)

Provide feedback

eye iconComments

Simon Horslen | 08/28/2025

Strongly Support

Amanda Salisbury | 08/28/2025

While I support changes to provide more clear guidance, I wanted to ask whether or not the availability of organs from living donors was factored into the order of priority presented here. I am a double living anonymous donor, but I would lean toward prioritizing single or multi organ patients whose donations must come from deceased donors. Single organ kidney and single organ liver patients have more avenues open for donation from family, friends, and Good Samaritans.

Terri Milton | 08/27/2025

Creating a standardized set of rules to implement a multi-organ allocation policy is needed.

Anonymous | 08/27/2025

Strongly Support

Anonymous | 08/27/2025

where does safety net kidney allocation fall in this ranking?

Anonymous | 08/27/2025

Support

Michigan Medicine | 08/27/2025

Support

Anonymous | 08/27/2025

Strongly Support

Anonymous | 08/27/2025

The effort to increase equity in access to highest quality organs is an important one. However, the inclusion of kidney-pancreas as part of the problem with multi-organ allocation - placing below several classes of kidney donors - further disadvantages the kidney-pancreas population.

Pancreas transplantation is the only solid organ transplant to decrease in frequency during an era where we are accomplishing record transplant volumes. Across all centers, pancreas transplant volumes have decreased. Simply put, there are fewer eligible pancreas donors than ever before, reflective of the prevalence of high BMI, medical comorbidities, and substance use. Less than 10% of donors meet consideration for pancreas donation, and even fewer proceed to transplantation. Therefore, when a viable pancreas is available for transplant, utilization should be prioritized by facilitating with simultaneous kidney-pancreas transplant.

I applaud the efforts to prioritize organ allocation for patients with "medical urgency". Pancreas transplant candidates, particularly patients with Type 1 diabetes and associated hypoglycemic events, remain at high medical urgency. Based on the rarity of pancreas transplant, frequency of pancreas utilization should not significantly impact access for medically urgent kidney recipients. Without prioritization to utilize pancreas allografts through SPK transplant, access for diabetic patients will continue to lack equity.