Histocompatibility Committee
The Histocompatibility Committee applies evolving science and technology in transplant immunology to develop, implement, and inform OPTN bylaws, policies, and clinical guidance for organ donation and transplantation. The Committee provides subject matter expertise to the OPTN for issues related to testing, matching, allocation, personnel qualifications, and other issues in transplant histocompatibility and immunology. The Committee’s goals are to promote patient safety, to strive to continuously improve clinical outcomes, and maximize the use of donated organs.
Current Projects
Review
Board approved and pending implementation
- Update Histocompatibility Bylaws
- Require Reporting of HLA Critical Discrepancies and Crossmatching Events to the OPTN
- Update Post-Transplant Histocompatibility Data Collection
Implemented
- Remove CPRA 99-100% Form for Highly Sensitized Kidney Candidates
- Update HLA Equivalency Tables, 2023
- Change Calculated Panel Reactive Antibody (CPRA) Calculation
- Require Notification of Human Leukocyte Antigen (HLA) Typing Changes (9/2021)
- HLA Equivalency Tables Update 2020 (12/2019)
- Update Human Leukocyte Antigen (HLA) Equivalency Tables
- Modify appointment process for histocompatibility committee vice chair (11/2019)
- Addressing HLA Typing Errors (2/2020)
- Review of HLA tables (7/2017)
- Histocompatibility labs policy and bylaws guidance 201701 (1/2017)
- Proposed Changes to the OPTN Bylaws Governing Histocompatibility Laboratories (Phase II) (9/2014)
Chair
- Dr. Gerald P Morris
- Histocompatibility and Immunogenetics Laboratory at UCSD
Vice Chair
- Dr. Kelley M Hitchman
- Histocompatibility and Immunogenetics Lab/University Health System
Liaison
- Jamie Panko
- UNOS Employee
- jamie.panko@unos.org
| Members | Organization | Position | End Term Date |
|---|---|---|---|
| Dr. Laurine M Bow | Histocompatibility and Immune Evaluation Laboratory at Yale | Region 1 Representative | 6/30/2025 |
| Dr. James S Bowman | Division of Transplantation, HHS | Ex Officio (non voting) | 6/30/2025 |
| Dr. Tiffany K Bratton | Histocompatibility Laboratory at Iowa Methodist Medical Center | Region 8 Representative | 6/30/2027 |
| Dr. Michael D Gautreaux | HLA/Immunogenetics Lab | Region 11 Representative | 6/30/2027 |
| Ms. Julie A Houp | Histocompatibility and Immunogenetics Laboratory CTI at UAB | Region 3 Representative | 6/30/2026 |
| Dr. Mike L Hurtik | Emory University Hospital | At Large | 6/30/2026 |
| Dr. Andres Jaramillo | Mayo Clinic in Arizona Histocompatibility Laboratory | Region 5 Representative | 6/30/2025 |
| Dr. Marilyn E Levi | Division of Transplantation, HHS | Ex Officio (non voting) | 6/30/2025 |
| Dr. John G Lunz | LifeLink Transplantation Immunology Laboratory | Ex Officio | 6/30/2025 |
| Helene McMurray | Tissue Typing Laboratory at Strong Memorial Hospital | Region 9 Representative | 6/30/2026 |
| Darryl C Nethercot | Lifesharing - A Donate Life Organization | At Large | 6/30/2026 |
| Ms. Stephanie L Osier | UF Health Shands Hospital | At Large | 6/30/2026 |
| Dr. Hemant K Parekh | Clinical Histocompatibility Lab at Ohio State University Medical Center | Region 10 Representative | 6/30/2026 |
| Dr. Ryan A Peña | Tufts Medical Center Laboratory | At Large | 6/30/2027 |
| Mr. David F Pinelli | Transplant Immunology Laboratory at Northwestern Memorial Hospital | Region 7 Representative | 6/30/2025 |
| Bobbie S Rhodes-Clark | Memorial Hermann-Texas Medical Center | Region 6 Representative | 6/30/2026 |
| Dr. Jerome G Saltarrelli | Memorial Hermann-Texas Medical Center | At Large | 6/30/2027 |
| Dr. Crystal Y Usenko | Histocompatibility Laboratory at Scott and White Memorial Hospital | Region 4 Representative | 6/30/2026 |
| Dr. Qingyong Xu | University of Pittsburgh Medical Center, Histocompatibility Laboratory, Presbyterian Clinical Laboratories | Region 2 Representative | 6/30/2025 |
- November 12, 2024 - Histo (PDF - 115 K)
- October 8, 2024 - Histo (PDF - 136 K)
- October 1, 2024 - Histo (PDF - 156 K)
- September 10, 2024 - Histo (PDF - 120 K)
- August 13, 2024 - Histo (PDF - 138 K)
- July 9, 2024 - Histo (PDF - 109 K)
- June 11, 2024 - Histo (PDF - 113 K)
- May 28, 2024 - Histo (PDF - 121 K)
- May 14, 2024 - Histo (PDF - 122 K)
- April 12, 2024 - Histo (PDF - 120 K)
- March 12, 2024 - Histo (PDF - 123 K)
- February 13, 2024 - Histo (PDF - 124 K)
- January 9, 2024 - Histo (PDF - 145 K)
- December 12, 2023 - Histo (PDF - 123 K)
- November 14, 2023 - Histo (PDF - 280 K)
- October 10, 2023 - Histo (PDF - 177 K)
- September 27, 2023 - Histo (PDF - 218 K)
- September 12, 2023 - Histo (PDF - 153 K)
- August 15, 2023 - Histo Donor and Recipient Forms Review Workgroup (PDF - 129 K)
- August 8, 2023 - Histo Discrepant Typings Subcommittee (PDF - 195 K)
- July 18, 2023 - Histo Donor and Recipient Forms Review Workgroup (PDF - 133 K)
- July 11, 2023 - Histo (PDF - 292 K)
- June 13, 2023 - Histo (PDF - 195 K)
- May 16, 2023 - Histo Donor and Recipient Forms Review Workgroup (PDF - 134 K)
- May 9, 2023 - Histo (PDF - 122 K)
- April 18, 2023 - Histo Donor and Recipient Forms Review Workgroup (PDF - 117 K)
- April 11, 2023 - Histo (PDF - 251 K)
- March 21, 2023 - Histo Donor and Recipient Forms Review Workgroup (PDF - 148 K)
- March 14, 2023 - Histo (PDF - 126 K)
- February 14, 2023 - Histo (PDF - 123 K)
- February 1, 2023 - Histo Discrepant HLA Typings Subcommittee (PDF - 120 K)
- January 10, 2023 - Histo (PDF - 160 K)
- December 13, 2022 - Histo (PDF - 135 K)
- November 8, 2022 - Histo (PDF - 169 K)
- October 7, 2022 - Histo (PDF - 172 K)
- September 13, 2022 - Histo (PDF - 129 K)
- August 9, 2022 - Histo (PDF - 151 K)
- July 12, 2022 - Histo (PDF - 143 K)
- June 14, 2022 - Histo (PDF - 243 K)
- May 10, 2022 - Histo (PDF - 144 K)
- April 5, 2022 - Histo (PDF - 241 K)
- March 8, 2022 - Histo (PDF - 241 K)
- March 2, 2022 - Histo Discrepant HLA Typings Subcommittee (PDF - 146 K)
- February 8, 2022 - Histo (PDF - 129 K)
- January 11, 2022 - Histo (PDF - 155 K)
Reports to the Board of Directors
- June 2017: Lab Bylaws and Policy Updates (PDF - 145 K)
- June 2016: Adding HLA DQA 1 Equivalences Table (PDF - 394 K)
Looking for something else? Contact us at unoscommunications@unos.org or (804) 782-4800. We maintain an archive of historical OPTN documents.